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Van Rooj et. al. demonstrated that the inhibition of miR-208a by systemic delivery of locked nucleic acid–modified antisense oligonucleotide prevented cardiac remodeling in a rat model of LV failure. This technology also prevented pathological myosin switching and cardiac remodeling, while improving cardiac function .
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Summary. Ejection fraction is a measurement doctors can use to help diagnose heart failure. A normal range is between 52% and 72% for males and between 54% and 74% for females. An ejection.
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